This course uses computational methods to analyze current problems and solutions in molecular biology research. Students are exposed to algorithms and tools available for both single gene and larger scale genome research. Emphasis is on practical application. Laboratories allow students to apply their knowledge to real-life molecular biology problems. This course routinely offers an opportunity to satisfy the Stony Brook Curriculum WRTD and Upper Division Writing Requirements for the Biology and Biochemistry majors. Students who intend to use the writing assignment in this course to satisfy these requirements must register for BIO 459 when they register for BIO 312.